In this paper I examine what I will call "the standard account" of intrinsic value as it appears in recent textbooks written by John Hospers, William Frankena, and Richard B. Brandt. I argue: (a) it is not clear whether a theory of intrinsic value can be developed along the lines of the standard account; (b) if one is to develop such a theory, one will need to introduce a notion of "basic intrinsic value" in addition to the notion of "intrinsic (...) value"; and (c) several different theories of intrinsic value may account for the same judgments concerning desirability, and it will be arbitrary to choose one of these theories over another. (shrink)

An attempt to analyse what it is for belief to be based on reasons becomes involved with questions about the goodness of reasons and the gettier examples. intuitions about knowledge and the "gettier effect" can be used to decide when reasoning has occurred and what reasoning there has been. explanation by reasons is not deterministic.

The authors sum up the central issue of ethics in the conduct of controlled clinical trials in these two paradoxes: 'first, it is unethical to use treatment the efficacy of which has not been examined scientifically; second, it is also unethical to examine the efficacy of treatment scientifically.' In this paper they set out to demonstrate how these antithetical statements apply in controlled trials conducted in psychiatric patients. In such trials the problem of obtaining informed consent may be acute, but (...) in these patients giving 'informed' consent might contribute to a further exacerbation of the illness. Nevertheless the problem cannot be evaded, and scientific judgments must be applied to treatment for it to be sound and improved for the further benefit of patients. These problems in the case of psychiatric controlled trials are a part of the methodology, and in Germany a new drug law has been drafted to attempt to clarify the issue. The authors briefly discuss its application, and its consequences if such a law were enacted. British psychiatrists have exactly the same problems to face but so far no attempts have been made to establish a legal framework. (shrink)

Here is a pioneering volume that explores adolescent homosexuality around the world. Social scientists examine the personal experiences of gay and lesbian teenagers from culture to culture and address the problems and obstacles these young people face. The changing contexts, values, and goals of societies worldwide are affecting how these adolescents adapt to being homosexual, and this compelling book gives keen insight into how changes in the United States contrast with changes elsewhere. A unique and thorough description of the identities, (...) situations, and relationships of homosexual teens in many societies, Gay and Lesbian Youth will help social scientists, health care professionals, counselors, gay teenagers, and their parents to better understand the similarities of the problems facing these youth, while recognizing the minor differences in their social and personal situations. How do the personal experiences of gay and lesbian teenagers vary from culture to culture? Here is the best, most complete description of the identities, situations, and relationships of homosexual teens in many societies. The changing contexts, values, and goals of societies worldwide are affecting how these adolescents adapt to being homosexual, and this compelling book gives keen insight into how changes in the United States contrast with changes elsewhere. Social scientists, health care professionals, counselors, gay teenagers, and their parents will better understand the similarities of the problems facing these youth, while recognizing the minor differences in their social and personal situations. These differences must be understood by interpreting the adaptations of gay and bisexual teenagers around the world. (shrink)

Purpose: Commenting on the transcript of a lecture. Findings: The document reconstructs the development of the original 1973 lecture by Heinz von Foerster into his best-known paper, On Constructing a Reality. Many aspects of that paper can be identified as being shaped through interaction with the audience. Implications: The lecture documented here was a forerunner of a central paper in constructivism.

(Statement of Responsibility) by Lewis Carroll ; with illustrations in colors.

The success of deep brain stimulation (DBS) for movement disorders and the improved understanding of the neurobiologic and neuroanatomic bases of psychiatric diseases have led to proposals to expand current DBS applications. Recent preclinical and clinical work with Alzheimer's disease and obsessive-compulsive disorder, for example, supports the safety of stimulating regions in the hypothalamus and nucleus accumbens in humans. These regions are known to be involved in addiction and overeating associated with obesity. However, the use of DBS targeting these areas (...) as a treatment modality raises common ethical considerations, which include informed consent, coercion, enhancement, threat to personhood, and manipulation of the reward center. Pilot studies for both of these conditions are currently investigational. If these studies show promise, then there is a need to address the ethical concerns related to the initiation of clinical trials including the reliability of preclinical evidence, patient selection, study design, compensation for participation and injury, cost-effectiveness, and the need for long-term follow-up. Multidisciplinary teams are necessary for the ethical execution of such studies. In addition to establishing safety and efficacy, the consideration of these ethical issues is vital to the adoption of DBS as a treatment for these conditions. We offer suggestions about the pursuit of future clinical trials of DBS for the treatment of addiction and overeating associated with obesity and provide a framework for addressing ethical concerns related to treatment. (shrink)

What role does non-genetic inheritance play in evolution? In recent work we have independently and collectively argued that the existence and scope of non-genetic inheritance systems, including epigenetic inheritance, niche construction/ecological inheritance, and cultural inheritance—alongside certain other theory revisions—necessitates an extension to the neo-Darwinian Modern Synthesis (MS) in the form of an Extended Evolutionary Synthesis (EES). However, this argument has been challenged on the grounds that non-genetic inheritance systems are exclusively proximate mechanisms that serve the ultimate function of calibrating organisms (...) to stochastic environments. In this paper we defend our claims, pointing out that critics of the EES (1) conflate non-genetic inheritance with early 20th-century notions of soft inheritance; (2) misunderstand the nature of the EES in relation to the MS; (3) confuse individual phenotypic plasticity with trans-generational non-genetic inheritance; (4) fail to address the extensive theoretical and empirical literature which shows that non-genetic inheritance can generate novel targets for selection, create new genetic equilibria that would not exist in the absence of non-genetic inheritance, and generate phenotypic variation that is independent of genetic variation; (5) artificially limit ultimate explanations for traits to gene-based selection, which is unsatisfactory for phenotypic traits that originate and spread via non-genetic inheritance systems; and (6) fail to provide an explanation for biological organization. We conclude by noting ways in which we feel that an overly gene-centric theory of evolution is hindering progress in biology and other sciences. (shrink)

Open peer commentary on the article “Luhmann and the Constructivist Heritage: A Critical Reflection” by Armin Scholl. Upshot: The comment starts with Buchinger’s assessment that Luhmann’s contribution to constructivism is original and inspiring, but raises more questions than answers. In three variations, the comment tries to show that Luhmann can indeed be viewed as a big question-generator and that his heritage for radical constructivism may lie in the original and inspiring effects these new and additional questions can produce.

The following study tries to elucidate the connection between the discourse of natural philosophy in the late eighteenth century and Wilhelm von Humboldt's anthropological, aesthetic and linguistic writings. The concepts of force, organism and, most significantly, of generation, as they were developed in the natural sciences, are shown to have strongly influenced Humboldt's philosophy. ;The first chapter reconstructs the scientific discussion about biological generation in the 18th century. At the end of the century, the widely accepted theory of preformationism is (...) challenged and replaced by the epigenetic model of generation, according to which each organism is individually produced by both parents and the workings of a formative force. ;The second chapter interprets the significance of this change for the philosophy of German Idealism, most notably in the works of Kant and Fichte. Epigenesis and its key concepts, such as "formative impulse" , organism and individuality is shown to provide a biological base for the idealist theories of subjectivity and freedom. ;The third chapter investigates Humboldt's involvement in the discourse and practice of natural philosophy during his studies at Gottingen and Jena. He discussed these problems frequently with his brother Alexander and his friends Schiller, Goethe and Fichte. His famous articles on the significance of sexual difference can be understood as a philosophical interpretation of his own scientific studies. ;The fourth chapter shows the main concepts of natural philosophy at work in Humboldt's mature writings about the philosophy of language. Against the backdrop of Goethe's scientific work, Humboldt's linguistic theory appears as an application of scientific notions to the "organism" of language. ;The fifth chapter concentrates on Humboldt's account of the mutual dependence and the mutual generation of language and thought. With his epigenetic account he tries to overcome the impasses of earlier 18th century theories of language. ;The last chapter focuses on the essential element in Humboldt's linguistic theory, the problem of articulation. Humboldt interprets articulation seen from the side of the subject as an act of violence, opposed to the material power of historically given languages. This interplay between violence and power is also shown to be at the center of Humboldt's hitherto unnoticed poetic works. (shrink)

Open peer commentary on the target article “Who Conceives of Society?” by Ernst von Glasersfeld. Excerpt: I will make the point that radical constructivism von Glasersfeld style unnecessarily plays only a passive or an inactive role. Quite obviously, I want to demonstrate that there is life for radical constructivism outside its seemingly irrelevant function in empirical social research and that it is possible to develop radical constructivism in designs with tangible consequences and effects for the cognitive routines in the social (...) sciences. In short, it is conceivable, despite “Who Conceives of Society?”, that radical constructivism matters. (shrink)

Purpose: Several accounts like Ernst von Glasersfeld's Who Conceives of Society? (2008) locate empirical research in the social sciences and radical constructivism in almost parallel universes. The main purpose of this paper is to argue for more inter-active relations and to stress the importance of establishing weak, medium and strong ties between radical constructivism and empirical social research in general. Findings: The article shows that that weak, medium and strong ties between radical constructivism and empirical research in the social sciences (...) can be established. Moreover, these weak, medium and strong ties play a crucial role for increasing and maintaining the relevance of radical constructivism within the social sciences and for contributing to the viability of radical constructivism in the long run. Implications: The most important consequence for radical constructivism lies in a new research agenda. In the course of this article weak, medium and strong ties to empirical research have been specified specifically and exclusively for the social sciences. But these specific links cannot be simply generalized or transferred to other disciplinary fields outside the social sciences. Since interactive links between radical constructivism and empirical research are currently missing in practically all disciplines, these weak, medium and strong links, as a new RC-agenda, have to be developed separately for each major scientific research arena. (shrink)

Background: Due to recent legislations on euthanasia and its current practice in the Netherlands and Belgium, issues of end-of-life medicine have become very vital in many European countries. In 2002, the Ethics Working Group of the German Association for Palliative Medicine (DGP) has conducted a survey among its physician members in order to evaluate their attitudes towards different end-of-life medical practices, such as euthanasia (EUT), physician-assisted suicide (PAS), and terminal sedation (TS). Methods: An anonymous questionnaire was sent to the 411 (...) DGP physicians, consisting of 14 multiple choice questions on positions that might be adopted in different hypothetical scenarios on situations of “intolerable suffering” in end-of-life care. For the sake of clarification, several definitions and legal judgements of different terms used in the German debate on premature termination of life were included. For statistical analysis t-tests and Pearson-correlations were used. Results: The response rate was 61% (n=251). The proportions of the respondents who were opposed to legalizing different forms of premature termination of life were: 90% opposed to EUT, 75% to PAS, 94% to PAS for psychiatric patients. Terminal sedation was accepted by 94% of the members. The main decisional bases drawn on for the answers were personal ethical values, professional experience with palliative care, knowledge of alternative approaches, knowledge of ethical guidelines and of the national legal frame. Conclusions: In sharp contrast to similar surveys conducted in other countries, only a minority of 9.6% of the DGP physicians supported the legalization of EUT. The misuse of medical knowledge for inhumane killing in the Nazi period did not play a relevant role for the respondents’ negative attitude towards EUT. Palliative care needs to be stronger established and promoted within the German health care system in order to improve the quality of end-of-life situations which subsequently is expected to lead to decreasing requests for EUT by terminally ill patients. (shrink)